This week, PharmaCompass continued its analysis of the top 10 fastest-growing drugs of 2016 by sales to evaluate the drugs that registered large sales growth. Please note that these are not the top-selling drugs, but are the top 10 drugs that registered the maximum growth in global sales over 2015. Interestingly, things didn’t appear that[…]
Chemical entities SHINE in the top 10 fastest-growing drugs of 2016
Anti-Retroviral / Anti-HIV, Blood Product, Chemotherapeutic / Anti-Neoplastic, Drug Research & Development API, FDA Approved 2014, FDA Approved 2015 Tags: GileadPfizer May 26, 2017
New Raltegravir Potassium Merck Agreement Proves to be a Major Improvement Over the Status Quo
Anti-Retroviral / Anti-HIV, Drug Research & Development API, Patent Expiration 2023 Tags: AIDSHIV Dec 21, 2015
Raltegravir potassium is a human immunodeficiency virus integrase strand transfer inhibitor. The drug is soluble in water and slightly soluble in ethanol and methanol as well. The pharmaceutically acceptable salt has been approved for the treatment of HIV-1. The multinational pharmaceutical, Merck has signed an agreement with MPP (Medicines Patent Pool) to license its intellectual property[…]
Sofosbuvir and Ledipasvir Offers 6 Week Hepatitis C Cure
Anti-Retroviral / Anti-HIV, Drug Research & Development API Tags: Hepatitis CSofosbuvir May 20, 2015
Sofosbuvir is popular in the pharmaceutical headlines as of late, with more positive news for the patient population with Hepatitis C. An NIH (National Institute of Allergy and Infectious Diseases) study released exciting data which showed the use of Sofosbuvir and Ledipasvir elicited a cure rate in only six weeks’ time for patients with the[…]
NRTI Lamivudine Looks Promising for AMD Treatment
Anti-Retroviral / Anti-HIV, Drug Research & Development API Tags: AMDHIV virus Jan 05, 2015
As an efficacious treatment for the HIV virus, the NRTI Lamivudine is now showing promise as a drug to combat age-related macular degeneration, known also as AMD. Nucleoside reverse transcriptase inhibitors, or NRTIs are the most commonly used class of anti-HIV medications and they are touted to successfully act on the enzyme reverse transcriptase, prohibiting[…]
Winning the Fight Against AIDS One Drug at a Time
Anti-Retroviral / Anti-HIV, Antiviral, Drug Research & Development API Tags: antiretroviral therapyHIV virus Dec 02, 2014
December 1, 2014 marked World AIDS Day, with roughly 40 million deaths worldwide over the past three decades attributed to this virulent disease. While there is no known cure for AIDS the advent of multiple drug regimens has made the treatment of the HIV virus which causes AIDS manageable for many patients globally. Unfortunately there[…]
Pyrazinamide is a Triple Threat to TB in HIV Patients
Anti-Retroviral / Anti-HIV, Antibacterial, Antibiotic, Drug Research & Development API Tags: HIV infectionHIV virus Aug 08, 2014
Midstage trial data of a Pyrazinamide cocktail to treat TB has offered encouraging news for patients with the HIV infection. Coined PaMZ, this drug trio includes Pyrazinamide and two antibacterial drugs, with results going into the Phase III trial looking promising. The antibacterial drugs are PA-824, which was initially developed by the Novartis and the[…]
Sofosbuvir Continues to Shine as Optimal Hepatitis C Treatment
Anti-Retroviral / Anti-HIV, Antiviral, Drug Research & Development API Tags: Hepatitis CSofosbuvir Jul 16, 2014
The FDA’s approval of Sofosbuvir in December 2013 paved the way for an exciting new treatment option for patients suffering from Hepatitis C. Known as the brand name Sovaldi, which is marketed by Gilead, Sofosbuvir is a unique nucleotide analog inhibitor that is the first Hepatitis C drug to demonstrate efficacy without the co-administration of[…]
FDA Accepts Peramivir NDA for Influenza Virus Treatment
Anti-Retroviral / Anti-HIV, Antiviral, Drug Research & Development API, NDA Mar 24, 2014
BioCryst Pharmaceuticals recently announced that the Peramivir NDA has been accepted for review by the FDA. The exciting news about the antiviral comes on the heels of a deadly flu season around the world, with the H1N1 virus being most commonly found. Widespread flu activity around the United States has caused alarm for practitioners and patients who[…]
Daclatasvir Awarded FDA Breakthrough Therapy Designation
Anti-Retroviral / Anti-HIV, Antiviral, FDA Breakthrough Therapy Status Mar 10, 2014
Daclatasvir has been in the pharmaceutical spotlight lately as part of a new hepatitis C cocktail. Bristol-Myers Squibb revealed their achievement of a breakthrough drug designation from the FDA for the Daclatasvir based combination hepatitis C treatment. The FDA’s decision to grant a breakthrough designation for this oral drug combination of Daclatasvir and Asunaprevir is[…]
Canada Approves Simeprevir for Hepatitis C
Anti-Retroviral / Anti-HIV, Antiviral, Drug Research & Development API, FDA Priority Status, Health Canada Approved 2013 Tags: Hepatitis Cribavirin Dec 04, 2013
On November 20, 2013 Health Canada revealed the approval of Simeprevir, known as the brand name GALEXOS, to treat hepatitis C. Janssen, the company that markets GALEXOS offered excitement for the approval of it’s once a day hepatitis C treatment. Simeprevir is designed to be administered adjunctively with both ribavirin and pegylated interferon, for the[…]
